N-Boc-N-bis(PEG4-acid)
This product is a multifunctional PEG reagent featuring a Boc-protected amine and two terminal carboxylic acids linked via PEG4 spacers. This design provides orthogonal reactivity, solubility, and flexibility, making it especially valuable for bioconjugation, orthogonal synthesis, and advanced drug delivery applications.
Key Features and Benefits:
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Boc-Protected Amine: Acid-labile protection enables controlled deprotection.
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Dual Carboxylic Acids: Support amide coupling with biomolecules.
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PEG4 Spacers: Provide solubility, hydrophilicity, and compact flexibility.
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Orthogonal Reactivity: Facilitates multi-step, selective conjugation strategies.
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High Purity: Ensures reproducible performance in advanced workflows.
Applications:
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Bioconjugation: Couples biomolecules with orthogonal reactive groups.
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Drug Delivery: Builds PEGylated scaffolds for therapeutic conjugates.
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Probe Development: Creates multifunctional probes for diagnostics.
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Synthetic Chemistry: Serves as a versatile intermediate for modular synthesis.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); deprotect Boc under acidic conditions.
This product integrates a Boc-protected amine with dual acids in PEG4 spacers, specifically offering solubility and orthogonal reactivity for advanced conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
