m-PEG7-amine
m-PEG7-amine is a high-purity monofunctional PEG linker featuring a terminal primary amine for efficient coupling with carboxylic acids, activated esters, or other electrophiles. The PEG7 spacer imparts excellent aqueous solubility, flexibility, and reduced steric hindrance, enabling efficient conjugation in both aqueous and organic systems. This versatile design is especially well-suited for bioconjugation, surface functionalization, and the preparation of PEGylated biomolecules.
Key Features and Benefits
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Primary Amine Group: Reacts readily with carboxyl, NHS ester, and other activated groups to form stable amide linkages.
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PEG7 Spacer: Enhances solubility, flexibility, and accessibility of the reactive amine while minimizing steric hindrance.
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Monofunctional Design: Ensures site-specific and controlled conjugation.
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High Purity: Supplied at >95% purity for consistent and reproducible results.
Applications
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PEGylation of proteins, peptides, and small molecules.
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Surface and nanoparticle functionalization.
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Hydrogel and biomaterial modification.
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Conjugation for drug delivery and diagnostic probes.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to preserve amine reactivity.
This product is a high-purity PEG linker with a terminal primary amine and a PEG7 spacer, providing excellent solubility and flexibility specifically for efficient, site-specific bioconjugation and material modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
