Mal-PEG-amine(Mal-PEG-NH2), MW 20K linker contains a maleimide group and an amine group. The PEG spacer increases the aqueous solubility of the resulting compound. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group reacts specifically with a thiol group to form a covalent C-S bond, enabling the bioconjugation with a thiol bearing molecules.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.