Mal-PEG-CH2CO2H, MW 3.4K group reacts specifically with a thiol group to form a covalent C-S bond, enabling the bioconjugation with a thiol bearing molecules. The acid can be used to conjugate with amine-bearing biomolecules such as lysine residue on the proteins and amine modified oligonucleotide and biopolymers. The PEG spacer increase the solubility of the resulting complex in aqueous media.
AxisPharm offers 4000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.