Mal-amido-PEG9-acid
This product is a heterobifunctional PEG9 linker with a thiol-reactive maleimide group and a terminal carboxylic acid. The PEG9 spacer provides hydrophilicity, flexibility, and medium-to-long chain spacing, making it an especially versatile reagent for bioconjugation, drug delivery, and advanced material applications.
Key Features and Benefits:
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Maleimide Group: Selectively reacts with thiols to form stable thioether bonds.
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Carboxylic Acid Group: Couples efficiently with amines for amide bond formation.
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PEG9 Spacer: Offers hydrophilicity, solubility, and steric flexibility.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Enables orthogonal conjugation for multifunctional design.
Applications:
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Bioconjugation: Attaches proteins, peptides, and biomolecules via thiol and amine handles.
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Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Material Science: Builds PEGylated scaffolds with dual-reactive handles.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve maleimide and acid reactivity.
This product combines thiol selectivity with amine-reactive carboxyl chemistry, making it an especially excellent tool for orthogonal conjugation and advanced bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
