m-PEG8-bromide
This product is a monofunctional PEG8 derivative with a terminal bromide group. The PEG8 spacer provides hydrophilicity and flexibility, while the bromide serves as a reactive alkylating handle for substitution or further functionalization in organic and bioconjugation chemistry.
Key Features and Benefits:
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Terminal Bromide: Reactive alkyl halide for nucleophilic substitution or coupling.
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PEG8 Spacer: Enhances solubility, flexibility, and reduces steric hindrance.
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High Purity: Ensures reproducibility in chemical and bioconjugation workflows.
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Versatile Reactivity: Suitable for introduction of thiols, amines, or other groups.
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Balanced Length: PEG8 chain provides moderate solubility and spacing.
Applications:
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Bioconjugation: Functionalize biomolecules through nucleophilic substitution.
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Drug Delivery: PEGylation to improve solubility and pharmacokinetics.
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Surface Modification: Attach PEG chains to nanoparticles, hydrogels, or polymers.
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Synthetic Chemistry: Precursor for further functionalized PEG derivatives.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO, acetonitrile) to preserve bromide reactivity.
This product offers a hydrophilic PEG spacer with a reactive halide end-group, making it an especially excellent intermediate for further derivatization and conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
