m-PEG8-azide
m-PEG8-azide is a high-purity monofunctional polyethylene glycol (PEG) derivative featuring a methoxy group on one end and an azide group on the other, connected by a PEG8 spacer. The azide group enables efficient copper-catalyzed azide–alkyne cycloaddition (CuAAC) or strain-promoted azide–alkyne cycloaddition (SPAAC) “click” reactions, providing robust and selective conjugation to alkyne-containing molecules. The PEG8 chain offers excellent hydrophilicity, flexibility, and spacing, making it especially suitable for a wide range of aqueous and organic applications.
Key Features
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Monofunctional PEG with terminal methoxy and azide groups
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Azide group compatible with CuAAC and SPAAC click chemistry
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PEG8 spacer enhances water solubility, flexibility, and biocompatibility
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High chemical purity ensures reproducible performance
Applications
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Click chemistry-based bioconjugation
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Antibody–drug conjugate (ADC) linker design
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Surface and nanoparticle functionalization
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Preparation of PEGylated small molecules and polymers
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Allow to warm to room temperature before opening
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Avoid repeated freeze–thaw cycles
This product is a methoxy-terminated PEG with an azide group for efficient click chemistry, connected by a PEG8 chain specifically for optimal solubility and flexibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
