m-PEG7-azide
m-PEG7-azide is a high-purity monofunctional polyethylene glycol derivative with a terminal azide group specifically for copper-catalyzed azide–alkyne cycloaddition (CuAAC) or strain-promoted azide–alkyne cycloaddition (SPAAC) click chemistry. The methoxy (m-) group on the opposite end provides a non-reactive terminus. The PEG7 spacer enhances solubility, flexibility, and reduces steric hindrance, enabling efficient conjugation in both aqueous and organic environments.
Key Features
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Terminal azide group for highly selective click chemistry reactions (CuAAC or SPAAC)
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Methoxy end group for controlled monofunctional reactivity
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PEG7 spacer improves hydrophilicity and reduces aggregation
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High chemical stability and purity for reproducible results
Applications
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Bioconjugation of biomolecules, peptides, and oligonucleotides
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Functionalization of nanoparticles and surfaces via click chemistry
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Synthesis of PEGylated probes, linkers, or drug delivery systems
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Orthogonal conjugation in complex synthetic workflows
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Warm to room temperature before opening
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Avoid repeated freeze–thaw cycles to maintain quality
This product is a monofunctional PEG linker with a terminal azide for click chemistry and a methoxy group for non-reactive termination, specifically connected via a PEG7 spacer for improved solubility and low steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
