m-PEG3-azide
m-PEG3-azide is a high-purity monofunctional polyethylene glycol (PEG) linker featuring an azide group for copper-catalyzed (CuAAC) or strain-promoted (SPAAC) azide–alkyne cycloaddition click chemistry. The PEG3 spacer specifically improves solubility, enhances flexibility, and reduces steric hindrance, enabling efficient bioconjugation in both aqueous and organic systems. This reagent is especially ideal for site-specific labeling, polymer and surface modification, and the development of multifunctional biomolecular probes.
Key Features and Benefits
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Azide Group: Compatible with CuAAC and SPAAC click chemistry for selective, high-yield conjugation.
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PEG3 Spacer: Enhances water solubility and reduces steric hindrance for improved reaction efficiency.
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Monofunctional Design: Allows precise, single-site modifications.
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High Purity: Supplied at >95% purity for reliable and reproducible results.
Applications
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Site-specific labeling of proteins, peptides, and antibodies.
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Preparation of click-ready surfaces, polymers, and nanoparticles.
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Synthesis of multifunctional probes and drug delivery systems.
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Bioorthogonal conjugation in live-cell or in vitro systems.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use with anhydrous solvents such as DMF or DMSO; avoid moisture to preserve reactivity.
This monofunctional PEG3 azide reagent offers a compact, hydrophilic spacer for efficient click chemistry, making it especially ideal for precise and versatile bioconjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
