Lipoamide-PEG-Mal, MW 5K contains the functional form of lipoic acid, lipoamide, via an amide bond and a maleimide end group. The lipoic acid is a co-factor that is used in biological systems such as the citric acid cycle. Maleimides are thiol-reactive between pH 6.5 to 7.5 and form thioester bonds. The hydrophilic PEG linkers increase the solubility of compounds in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
