Iodoacetamido-PEG8-acid CAS:1698019-88-3 contains an iodoacetamido functional group (-IA) attached to the PEG chain, which can covalently bind to sulfhydryl groups (-SH) of proteins, peptides, and other biomolecules, forming stable thioether bonds.
Iodoacetamido-PEG8-acid has been widely utilized in the development of novel drug delivery systems, protein modification, and bioconjugation. The compound can be used to modify proteins or peptides by specifically reacting with cysteine residues, which are present in many biologically active molecules. This modification improves the stability, solubility, and pharmacokinetic properties of the modified molecules, thus enhancing their therapeutic efficacy and reducing potential side effects.
Iodoacetamido-PEG8-acid can be utilized in the development of novel drug delivery systems, such as liposomes, micelles, and nanoparticles. By attaching Iodoacetamido-PEG8-acid to the surface of these delivery vehicles, it is possible to introduce targeting moieties or to covalently attach therapeutic agents, resulting in enhanced drug delivery and improved therapeutic outcomes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
