Hyaluronic Acid Biotin (MW 250K) is lyophilized powder with biotin covalently attached to high-molecular-weight hyaluronic acid where the conjugated biotin specifically enables binding to streptavidin for affinity isolation, cell tracing and CD44 receptor detection. It is widely applied in tissue engineering, sustained drug delivery and extracellular matrix research.
Key Features and Benefits
- Biotin Functionalization: Provides biotin groups for strong and specific interactions with avidin and streptavidin systems.
- MW 250K: Offers moderate molecular weight for especially convenient processing and versatile biomaterial development.
- HA-Based Material: Retains the hydrophilic polysaccharide backbone of hyaluronic acid.
- Affinity Binding: Supports avidin-, streptavidin-, and neutravidin-based binding platforms.
- Versatile Modification: Enables immobilization, labeling, surface functionalization, and molecular assembly.
- Biomaterial Platform: Combines HA properties with biotin-mediated affinity interactions for functional material design.
Applications
- Affinity Binding: Supports avidin-biotin and streptavidin-biotin binding systems.
- Bioconjugation: Enables assembly with biotin-binding proteins, probes, ligands, and functional materials.
- Labeling and Detection: Supports HA tracking, detection, and analytical research.
- Surface Modification: Enables immobilization of HA onto compatible biotin-binding surfaces.
- Biomaterials: Supports hydrogels, coatings, matrices, scaffolds, and other functional HA-based systems.
Storage and Handling
- Storage: Store at –20 °C in a fully sealed container under dry and dark conditions.
- Handling: Protect from moisture, light, and excessive heat to maintain polymer integrity and biotin functionality.
Hyaluronic Acid Biotin (HA-Biotin), MW 250K combines moderate-molecular-weight HA with biotin functionality that specifically supports affinity binding, bioconjugation, labeling, surface modification, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
