.Hyaluronic Acid Biotin (HA-Biotin), MW 10K is water-soluble lyophilized powder specifically formed by covalently linking biotin (vitamin B7) to medium-molecular hyaluronic acid. Compared with 3K low-molecular HA-biotin, it features weaker tissue penetration but especially superior water retention and stable hydrogel-forming capacity. The biotin tag specifically enables specific binding to streptavidin for affinity capture, cell tracking and HA receptor detection.
Key Features and Benefits
- Biotin Functionalization: Provides biotin groups for high-affinity avidin and streptavidin interactions.
- MW 10K: Offers low molecular weight for convenient processing and flexible experimental design.
- HA-Based Material: Uses hyaluronic acid as the hydrophilic polysaccharide backbone.
- Affinity Binding: Supports avidin- and streptavidin-based experimental platforms.
- HA Probe: Provides a functional tool for studying HA-binding proteins and molecular interactions.
- Versatile Platform: Supports labeling, detection, immobilization, and molecular assembly.
Applications
- HA-Binding Protein Research: Supports detection and investigation of hyaluronan-binding proteins.
- Affinity Binding: Supports avidin-biotin and streptavidin-biotin systems.
- Labeling and Detection: Enables affinity-based detection and analytical research.
- Bioconjugation: Supports assembly with biotin-binding proteins, probes, and functional components.
- Surface Modification: Enables immobilization and development of functional HA-based surfaces.
Storage and Handling
- Storage: Store at –20 °C in a fully sealed container under dry and dark conditions.
- Handling: Protect from moisture, light, and excessive heat to maintain polymer integrity and biotin functionality.
Hyaluronic Acid Biotin (HA-Biotin), MW 10K combines low-molecular-weight HA with versatile biotin functionality that specifically supports affinity detection, HA-binding studies, bioconjugation, immobilization, and functional biomaterial research and is widely applied in biomaterial fabrication, targeted drug delivery, cell biology assays and regenerative research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
