HS-PEG-COOH, MW 1K
This product is a high-purity heterobifunctional PEG reagent with a terminal thiol group and a carboxylic acid, offering versatile reactivity and solubility specifically for bioconjugation and surface modification.
Key Features and Benefits
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Thiol Group (–SH) – Enables efficient conjugation to maleimide, gold, or other thiol-reactive surfaces.
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Carboxylic Acid Group (–COOH) – Provides a reactive site for amide bond formation with primary amines.
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PEG (MW 1K) – Improves solubility, flexibility, and biocompatibility while reducing steric hindrance.
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High Purity – Ensures reproducibility in sensitive applications including protein modification and nanomaterials.
Applications
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Conjugation of proteins, peptides, or antibodies via thiol and carboxyl chemistry
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Functionalization of nanoparticles, quantum dots, or gold surfaces
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PEGylation to enhance solubility and reduce aggregation
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Use in drug delivery systems, diagnostics, and biomaterials engineering
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Prepare solutions in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides dual reactivity through a thiol group for surface or protein attachment and a carboxyl group for amide coupling, with a PEG spacer that specifically improves solubility, flexibility, and biocompatibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
