Amino-PEG12-alcohol
This product is a bifunctional PEG linker with a terminal primary amine and a terminal hydroxyl group connected by a PEG12 spacer. It provides excellent solubility and flexibility, specifically enabling versatile bioconjugation and surface modification strategies.
Key Features and Benefits
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Primary Amine: Couples efficiently with carboxyls, NHS esters, and activated linkers.
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Hydroxyl Group: Provides an additional handle for further derivatization.
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PEG12 Spacer: Enhances solubility, biocompatibility, and molecular spacing.
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Dual Functionality: Combines amine reactivity with hydroxyl versatility.
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High Purity: Ensures reliable performance in synthetic and bioconjugation workflows.
Applications
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Bioconjugation: Couples to proteins, peptides, or small molecules via amine chemistry.
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Probe Development: Builds multifunctional scaffolds for diagnostics and imaging.
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Drug Delivery: Serves as a PEGylated linker for therapeutic conjugates.
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Material Science: Functionalizes polymers, nanoparticles, and surfaces with dual groups.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain reactivity.
This product integrates a reactive primary amine and hydroxyl group into a PEG12 scaffold, specifically providing a long, flexible, and biocompatible linker for bioconjugation and advanced material design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.