Gly-Gly-Gly-PEG2-azide (CAS: 2222277-20-3) is a versatile linker used in bioconjugation and drug development. It features a tri-glycine peptide connected to a PEG2 spacer, ending with an azide group for click chemistry reactions. Its design enhances water solubility, flexibility, and bioorthogonal reactivity.
Key Features:
- Azide Group: Supports copper-catalyzed and strain-promoted click chemistry.
- Tri-Glycine Peptide: Provides a flexible, hydrophilic linker structure.
- PEG2 Spacer: Improves solubility and reduces steric hindrance.
- Molecular Formula: C₁₂H₂₃N₇O₅
- Molecular Weight: 345.35 g/mol
Applications:
- Antibody-Drug Conjugates (ADCs): Enables drug attachment for targeted cancer therapy.
- Bioconjugation: Links biomolecules for precise and site-specific assembly.
- Chemical Biology Research: Facilitates protein labeling, drug delivery, and molecular assembly.
This linker offers efficient conjugation with azide-reactive molecules, making it essential for biopharmaceutical development and advanced research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
