Fmoc-NH-PEG5-amine
This product is a PEG linker containing an Fmoc-protected amine, a PEG5 spacer, and a terminal free amine. It enables orthogonal conjugation through selective Fmoc deprotection while offering solubility and medium-length flexibility for bioconjugation and synthesis.
Key Features and Benefits
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Fmoc-Protected Amine: Allows selective deprotection for orthogonal reactivity.
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Terminal Amine: Couples with carboxyls, NHS esters, or activated linkers.
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PEG5 Spacer: Provides solubility and moderate chain length.
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Dual Reactivity: Combines orthogonal amine protection with a free amine group.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Links PEG chains to biomolecules under orthogonal control.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with dual reactive amine handles.
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Organic Synthesis: Serves as an intermediate for custom linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates orthogonal Fmoc protection with a terminal free amine in a PEG5 scaffold, specifically offering controlled and versatile conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
