FmocNH-PEG3-amine
This product is a heterobifunctional PEG linker containing an Fmoc-protected amine at one end and a free amine at the other, separated by a PEG3 spacer. It specifically enables stepwise synthesis, amide coupling, and bioconjugation with improved solubility and flexibility.
Key Features and Benefits
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Dual Amines: One Fmoc-protected amine for controlled deprotection, one free amine for immediate conjugation.
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PEG3 Spacer: Enhances solubility and provides moderate spacing between reactive groups.
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Orthogonal Reactivity: Supports sequential modification and stepwise synthetic strategies.
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Versatile Linker: Suitable for peptide synthesis, drug delivery, and bioconjugation.
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High Purity: Ensures reproducibility and reliability in demanding workflows.
Applications
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Peptide Synthesis: Fmoc group enables controlled stepwise assembly.
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Bioconjugation: Couples to carboxyl- or ester-functionalized biomolecules.
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Drug Delivery: Provides PEG scaffolds with dual amine handles for multifunctional conjugates.
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Diagnostics: Functionalizes biomolecules for probe and assay development.
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Organic Synthesis: Serves as an intermediate for modular PEG linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates a free amine and an Fmoc-protected amine across a PEG3 spacer, specifically providing orthogonal reactivity, solubility, and flexibility for peptide synthesis and advanced bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
