Fmoc-PEG3-NHS ester is a versatile PEG linker with a protected amine. The PEG spacer enhances water solubility, making it ideal for bioconjugation applications. The NHS ester reacts with primary amines to form stable amide bonds, while the Fmoc group can be removed under basic conditions to expose a free amine for further reactions.
Key Features
- Dual Functional Groups: Includes an Fmoc-protected amine and an NHS ester for flexible reactivity.
- Water Solubility: The PEG spacer ensures good solubility in aqueous environments.
- Reactivity: The NHS ester attaches to primary amines, while the Fmoc group can be removed to reveal a free amine.
Applications
- Bioconjugation: Facilitates the attachment of biomolecules through amide bond formation.
- Drug Development: Acts as a linker for creating antibody-drug conjugates (ADCs).
- Material Science: Enhances surface modifications with PEGylated compounds for improved biocompatibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
