Fmoc-NH-PEG8-CH2COOH
This product is a PEG linker containing an Fmoc-protected amine, a PEG8 spacer, and a terminal carboxymethyl group. It specifically enables orthogonal conjugation, offering solubility, medium chain length, and dual reactivity for bioconjugation and synthesis.
Key Features and Benefits
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Fmoc-Protected Amine: Allows selective deprotection for orthogonal conjugation.
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Carboxymethyl Group: Couples efficiently with amines to form stable amide bonds.
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PEG8 Spacer: Provides solubility and medium flexibility.
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Dual Reactivity: Combines protected amine chemistry with carboxyl coupling.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Links PEG chains to biomolecules with orthogonal control.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEG scaffolds with solubility and dual reactive groups.
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Organic Synthesis: Serves as a versatile intermediate for modular linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates Fmoc-protected amine chemistry with carboxymethyl functionality in a PEG8 scaffold, specifically offering solubility and orthogonal conjugation versatility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
