Fmoc-Glu(biotinyl-PEG)-OH CAS: 817169-73-6 serves as a versatile biotinylation reagent, excelling in solubility for solid-phase peptide synthesis. It outperforms FMOC-Lys(biotin)-OH in both organic solvents and water. The PEG spacer reduces hindrance, enhancing biotin binding and minimizing non-specific interactions. Equipped with a terminal Fmoc group, it readily reacts with amines when activated with EDC or HATU. Basic deprotection results in a free amine, ideal for further conjugations.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.