exo-BCN-PNP carbonate (CAS: 1380006-72-3) is a highly effective reagent for bio-orthogonal chemistry and bioconjugation. It contains two reactive groups. The strained BCN group allows for rapid, catalyst-free SPAAC reactions. Meanwhile, the PNP carbonate reacts smoothly with primary amines, making it easy to attach to biomolecules and surfaces.
Additionally, its structure ensures high selectivity and excellent reactivity. Because of this, it is widely used in drug delivery, biomolecule labeling, and material science.
Key Features
- Two Reactive Groups – BCN enables fast SPAAC, while PNP carbonate supports amine coupling.
- Metal-Free Click Chemistry – Reacts quickly without requiring copper catalysts.
- Highly Selective – Ensures clean and efficient modifications.
- Broad Applications – Works in bioconjugation, drug delivery, and material science.
- Reliable & Efficient – Delivers consistent and reproducible results.
Applications
- Bio-Orthogonal Click Chemistry – Supports rapid and efficient SPAAC reactions.
- Protein & Peptide Labeling – Modifies biomolecules for research and therapeutic use.
- Surface Functionalization – Enhances surfaces for biomedical and material science applications.
- Targeted Drug Delivery – Plays a key role in advanced therapeutic research.
- Nanoparticle Engineering – Improves nanoparticle stability and reactivity.
Conclusion
To sum up, exo-BCN-PNP carbonate is an excellent reagent for bio-orthogonal chemistry and bioconjugation. Its dual-reactive design enables fast and selective modifications, ensuring efficiency in research applications. Furthermore, its copper-free click chemistry and strong amine coupling abilities make it a top choice for biomolecule labeling, drug delivery, and nanotechnology. Because of its strong reactivity and broad utility, this reagent consistently delivers reliable results.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.