endo-BCN-PEG2-alcohol
This product is a heterobifunctional linker featuring an endo-bicyclononyne (BCN) group for copper-free SPAAC click chemistry and a terminal hydroxyl group for further derivatization. The PEG2 spacer provides hydrophilicity and compact flexibility, making it especially ideal for probe design, bioconjugation, and drug delivery.
Key Features and Benefits:
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Endo-BCN Group: Enables catalyst-free SPAAC click reactions with azides.
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Hydroxyl Group: Serves as a versatile handle for further modification.
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PEG2 Spacer: Provides solubility and minimizes steric hindrance.
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Compact Design: Supports close-range conjugation strategies.
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High Purity: Ensures reliable performance in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules through bioorthogonal BCN click chemistry.
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Probe Development: Builds BCN-functionalized probes for imaging and diagnostics.
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Drug Delivery: Provides PEGylated scaffolds for improved solubility and stability.
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Synthetic Chemistry: Intermediate for advanced linker development.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect BCN group from prolonged light exposure.
This product combines SPAAC-ready BCN functionality with a hydroxyl group in a PEG2 scaffold, specifically offering solubility and versatility for synthetic and bioconjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
