endo-BCN-PEG1-alcohol
This product is a heterobifunctional linker featuring an endo-bicyclononyne (BCN) group for copper-free SPAAC click chemistry and a terminal hydroxyl group for further derivatization. The short PEG1 spacer provides hydrophilicity and compact flexibility, making it especially useful in probe design, bioconjugation, and drug delivery.
Key Features and Benefits:
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Endo-BCN Group: Enables catalyst-free SPAAC click chemistry with azides.
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Hydroxyl Group: Serves as a versatile handle for further functionalization.
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PEG1 Spacer: Provides hydrophilicity with minimal steric bulk.
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Compact Design: Ideal for close-range conjugation strategies.
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High Purity: Ensures consistent results in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules via SPAAC click chemistry.
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Probe Development: Builds BCN-functionalized probes for imaging and diagnostics.
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Drug Delivery: Supports compact, PEGylated conjugates with click-ready handles.
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Synthetic Chemistry: Serves as a precursor for derivatized BCN linkers.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect BCN group from prolonged light exposure.
This product combines click-ready BCN functionality with a hydroxyl handle in a compact PEG1 scaffold, specifically offering solubility and synthetic versatility for advanced applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
