DMPE-mPEG, MW 1K is an amphiphilic phospholipid-PEG conjugate containing a hydrophobic DMPE lipid anchor and hydrophilic 1K methoxy-terminated PEG chain that specifically supports PEGylation, lipid assembly, liposome formulation, lipid nanoparticle research, and biomaterial development.
Key Features and Benefits
- Amphiphilic Structure: DMPE-mPEG combines a hydrophobic phospholipid anchor with a hydrophilic mPEG chain.
- mPEG MW 1K: The 1K methoxy-terminated PEG segment provides hydrophilic character for lipid-based formulations.
- DMPE Lipid Anchor: Dimyristoyl phosphatidylethanolamine specifically provides two saturated C14 lipid chains for incorporation into lipid membranes and assemblies.
- Methoxy-Terminated PEG: The terminal methoxy group provides a nonreactive PEG end group without additional conjugation functionality.
- PEGylated Lipid Platform: The mPEG chain introduces a hydrophilic polymer segment into DMPE-containing lipid systems.
- Lipid Assembly Capability: The amphiphilic structure specifically supports incorporation into liposomes, lipid nanoparticles, and related lipid assemblies.
- Surface PEGylation: DMPE anchoring enables presentation of hydrophilic PEG chains on compatible lipid surfaces.
- Formulation Versatility: The phospholipid-PEG architecture specifically supports diverse lipid-based and nanoscale research formulations.
Applications
- Lipid Nanoparticle Research: Researchers use DMPE-mPEG, MW 1K in PEG-containing lipid nanoparticle formulations.
- Liposome Research: Supports incorporation of mPEG chains into liposomes and other phospholipid assemblies.
- PEGylation Research: Provides a phospholipid-anchored PEG component for studying PEG-modified lipid systems.
- Nanoparticle Formulation: Supports development and evaluation of lipid-based nanoparticles and nanoscale formulations.
- Lipid Assembly Research: Enables investigation of phospholipid-PEG organization, self-assembly, and material properties.
- Surface Modification: Supports PEG modification of compatible lipid membranes and hydrophobic surfaces.
- Drug Delivery Research: Provides an amphiphilic phospholipid-PEG component for experimental delivery-system development.
- Biomaterial Research: Supports development of PEGylated lipid materials and functional nanoscale biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DMPE-mPEG, MW 1K combines a DMPE lipid anchor with a hydrophilic methoxy-terminated PEG chain and specifically supports PEGylation, lipid nanoparticles, liposomes, surface modification, drug delivery, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
