Diethyl 4-bromobutylphosphonate
This product is a small-molecule reagent containing a bromobutyl chain and a phosphonate ester group. The bromide acts as an excellent leaving group for nucleophilic substitution, while the phosphonate ester serves as a versatile functional handle for further derivatization. Its bifunctional nature makes it an especially valuable intermediate in medicinal chemistry, probe development, and organophosphorus synthesis.
Key Features and Benefits
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Bromobutyl Group: Provides a reactive site for nucleophilic substitution.
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Phosphonate Ester: Functions as a stable, modifiable handle for derivatization.
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Dual Reactivity: Combines alkyl halide substitution with organophosphorus chemistry.
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Versatile Intermediate: Useful in synthetic, medicinal, and chemical biology research.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Medicinal Chemistry: Builds phosphonate-containing drug candidates.
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Probe Development: Serves as a scaffold for radiolabeling or tagging strategies.
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Organic Synthesis: Functions as a precursor to phosphonic acids or derivatives.
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Chemical Biology: Supports the design of reactive linkers and enzyme inhibitors.
Storage and Handling
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Storage: Store at 2–8 °C in a sealed container, protected from light and moisture.
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Handling: Handle under dry conditions; bromides are reactive toward nucleophiles.
This product combines alkyl halide and phosphonate chemistry in one scaffold, specifically offering versatility for drug discovery, labeling, and synthetic research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
