DBCO-PEG2-tris-triacid, with CAS number 2374970-03-1, is a multifaceted chemical compound widely used in bioconjugation. This compound is uniquely composed, featuring a dibenzocyclooctyne (DBCO) group, a polyethylene glycol (PEG) spacer, and a tris-triacid group. Each component plays a critical role in the compound’s functionality and application.
The DBCO group, a cornerstone of DBCO click chemistry, is known for its high reactivity. It can undergo a click reaction with azide groups, forming stable triazole linkages. This reaction is a staple in bioconjugation, commonly used to attach molecules like proteins or peptides to surfaces, nanoparticles, or other molecules. DBCO’s specificity and rapid reaction rate make it an invaluable tool in the field.
The PEG spacer in DBCO-PEG2-tris-triacid is integral for the solubility and stability of the compound in various biological applications. Its presence enhances the compound’s functionality and applicability in diverse environments. Additionally, the tris-triacid group not only contributes to the compound’s solubility and stability but also offers a versatile platform for attaching other functional groups, such as amino groups or carboxylic acid groups.
Furthermore, the utility of DBCO in bioconjugation is complemented by the chemistry of DBCO NHS, providing additional avenues for bioconjugation and molecular design.
DBCO-PEG2-tris-triacid represents a crucial tool in bioconjugation, enabling the attachment of molecules to surfaces or other molecules through the highly reactive and versatile DBCO group. The combination of the PEG spacer and tris-triacid group in this compound makes it exceptionally versatile for a range of biological applications, further exemplified by the extensive range of DBCO linker available for research and development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.