Cyanine3 Tetrazine (CAS: 2183473-57-4)
Cyanine3 Tetrazine, or Cy3 Tetrazine, is a fluorescent dye that combines the bright fluorescence of Cyanine3 with a reactive tetrazine group. It enables fast and specific bioorthogonal labeling, making it ideal for a variety of imaging and bioconjugation applications.
Key Features:
- Bright Fluorescence:
- Excitation: 555 nm
- Emission: 570 nm
- Suitable for high-contrast imaging.
- Tetrazine Reactivity:
- Reacts quickly with strained alkenes like trans-cyclooctenes via inverse electron demand Diels-Alder (iEDDA) reactions.
- Ensures precise and rapid conjugation.
- Versatile Solubility:
- Works in both aqueous environments and organic solvents like DMSO or acetonitrile.
Applications:
- Bioorthogonal Labeling:
- Specifically tags biomolecules without interfering with biological systems.
- Fluorescence Imaging:
- Visualizes labeled proteins, nucleic acids, or small molecules for research and diagnostics.
- Bioconjugation:
- Plays a key role in click chemistry reactions for creating labeled conjugates.
Cy3 Tetrazine is a powerful tool for molecular imaging and chemical biology, offering bright fluorescence, rapid conjugation, and high specificity for biomolecule labeling.
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