CbzNH-PEG3-CH₂CH₂NH₂ (CAS: 863973-20-0) is a polyethylene glycol (PEG) derivative featuring a carbobenzyloxy (Cbz)-protected amine at one end and a free amine at the other. The PEG spacer enhances aqueous solubility, making it valuable in various chemical and biomedical applications.
Key Features:
- Functional Groups: Cbz-protected amine and free amine
- Solubility: Soluble in water and common organic solvents
Applications:
- Peptide Synthesis: The Cbz group protects the amine during synthesis and can be removed under acidic conditions to reveal the free amine for further reactions.
- Bioconjugation: The free amine reacts with carboxylic acids or activated esters to form stable amide bonds, facilitating the conjugation of biomolecules.
- Drug Delivery Research: The PEG spacer improves solubility and biocompatibility, aiding in the development of drug delivery systems.
Handling and Storage:
- Storage Conditions: Store at -20°C in a dry, light-protected environment.
- Handling Precautions: Use personal protective equipment and handle in a well-ventilated area.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.