Cbz-N-Amido-PEG8-CH2COOH
This product is a high-purity PEG linker featuring a carbobenzoxy (Cbz)-protected amine and a terminal carboxylic acid group, connected by a PEG8 spacer. This design enables selective deprotection, excellent solubility, and especially versatile use in bioconjugation, drug delivery, and surface modification.
Key Features and Benefits
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Cbz-Protected Amine – Provides selective deprotection under hydrogenolysis for orthogonal functionalization.
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Carboxylic Acid Group – Reactive site for amide coupling with primary amines or peptide backbones.
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PEG8 Spacer – Improves solubility, reduces steric hindrance, and provides flexibility in conjugates.
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High Purity – Ensures reliability for pharmaceutical, diagnostic, and biomaterials applications.
Applications
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Amide bond formation for peptide, protein, and antibody conjugation
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Use as a linker in drug delivery systems and PEGylated therapeutics
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Surface functionalization and biomaterial modification
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Scaffold for dual-functional linker strategies requiring orthogonal protection
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product is a PEG linker with a Cbz-protected amine and a terminal carboxyl group on a PEG8 spacer, offering solubility, flexibility, and selective reactivity for especially efficient conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
