Cbz-N-Amido-PEG2-acid
This product is a bifunctional PEG2 linker with a Cbz-protected amide and a terminal carboxylic acid. The short PEG2 spacer improves solubility and reduces steric hindrance, while the Cbz group provides stable carbamate protection for orthogonal synthesis.
Key Features and Benefits:
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Cbz-Protected Amide: Stable carbamate protecting group for controlled deprotection.
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Carboxylic Acid Group: Couples with amines to form stable amide bonds.
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PEG2 Spacer: Compact chain providing solubility and flexibility.
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High Purity: Ensures reproducibility in bioconjugation and synthetic workflows.
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Orthogonal Design: Supports stepwise and selective conjugation strategies.
Applications:
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Bioconjugation: Attach biomolecules with precise PEG spacing.
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Drug Delivery: Enhances solubility and stability of therapeutic payloads.
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Surface Modification: Functionalizes nanoparticles, hydrogels, or polymers.
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Synthetic Chemistry: Useful intermediate in PEGylated scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.
This product provides a short PEG spacer with Cbz-protected and carboxylic acid functionalities, making it an especially versatile tool for orthogonal conjugation and synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
