Carboxy-PEG2-sulfonic acid
This product is a heterobifunctional PEG linker containing a terminal carboxyl group, a PEG2 spacer, and a sulfonic acid group. It specifically enables dual reactivity, offering solubility, ionic character, and orthogonal functionality for bioconjugation and material applications.
Key Features and Benefits
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Carboxyl Group: Couples with primary amines to form stable amide bonds.
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Sulfonic Acid: Provides ionic character and functionalization for charged environments.
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PEG2 Spacer: Enhances solubility while maintaining compact spacing.
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Dual Reactivity: Combines carboxyl conjugation with sulfonic functionality.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Couples biomolecules through amide chemistry while introducing sulfonic functionality.
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Probe Development: Builds dual-functional probes with ionic and conjugation handles.
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Drug Delivery: Provides PEG scaffolds with solubility and charged properties.
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Material Science: Functionalizes nanoparticles, polymers, and surfaces with carboxyl and sulfonic groups.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve in aqueous buffers or polar solvents; avoid prolonged exposure to moisture.
This product integrates carboxyl conjugation and sulfonic functionality in a PEG2 scaffold, specifically offering solubility and ionic versatility for conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
