Bromoacetamide-PEG3-propargyl is widely used for thiol labelling and thiol capping reagent. It undergoes a fast nucleophilic substitution reaction with thiol. the propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The PEG spacer increase the solubility of the resulting complex in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.