Bromo-PEG5-phosphonic acid
This product is a heterobifunctional linker featuring a reactive bromoalkyl group for nucleophilic substitution and a terminal phosphonic acid for chelation or surface binding. The PEG5 spacer improves solubility, flexibility, and accessibility, making it especially effective for bioconjugation, material science, and biomedical research.
Key Features and Benefits:
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Bromo Group: Enables substitution with nucleophiles for versatile derivatization.
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Phosphonic Acid: Provides strong chelating and surface-binding properties.
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PEG5 Spacer: Enhances hydrophilicity and steric flexibility.
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Dual Reactivity: Supports multifunctional, stepwise conjugation strategies.
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High Purity: Ensures reproducibility in demanding workflows.
Applications:
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Bioconjugation: Couples biomolecules through nucleophilic substitution and phosphonate chemistry.
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Drug Delivery: Provides PEGylated scaffolds with reactive handles.
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Material Science: Functionalizes nanoparticles, surfaces, and polymers.
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Biomedical Research: Supports coordination chemistry and targeted conjugates.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect from prolonged moisture exposure.
This product integrates a reactive bromo group with a phosphonic acid handle in a PEG5 scaffold, specifically offering solubility and versatility for advanced conjugation and material modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.