Bromo-PEG2-phosphonic acid
This product is a heterobifunctional PEG linker containing a reactive bromoalkyl group for nucleophilic substitution and a terminal phosphonic acid for chelation or surface modification. The PEG2 spacer imparts hydrophilicity and compact flexibility, making it especially useful in bioconjugation, material science, and biomedical research.
Key Features and Benefits:
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Bromo Group: Provides reactivity for substitution with nucleophiles.
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Phosphonic Acid: Strong chelating and surface-binding functionality.
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PEG2 Spacer: Improves solubility while maintaining compact spacing.
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Dual Reactivity: Supports orthogonal conjugation strategies.
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High Purity: Ensures reproducible results in advanced workflows.
Applications:
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Bioconjugation: Couples biomolecules through nucleophilic substitution and phosphonate chemistry.
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Material Science: Functionalizes surfaces, polymers, and nanoparticles.
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Drug Delivery: Provides PEGylated scaffolds with chelating handles.
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Biomedical Research: Supports targeted conjugation and coordination chemistry.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid prolonged exposure to moisture.
This product combines nucleophilic substitution reactivity with phosphonic acid functionality in a compact PEG2 scaffold, specifically offering versatility for conjugation and surface modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
