t-Boc-N-Amido-PEG5-alcohol
This product is a heterobifunctional PEG linker containing a Boc-protected amide group, a PEG5 spacer, and a terminal hydroxyl group. The Boc group specifically provides orthogonal protection for controlled deprotection and further functionalization. The hydroxyl group serves as a versatile handle for derivatization, while the PEG5 chain enhances solubility and flexibility, making this reagent well suited for bioconjugation and material modification.
Key Features and Benefits
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Boc-Protected Amide: Allows selective deprotection and stepwise conjugation.
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Hydroxyl Group: Provides a handle for chemical modification.
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PEG5 Spacer: Improves solubility and reduces steric hindrance.
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Versatile Scaffold: Supports multifunctional conjugation strategies.
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High Purity: Produced to ≥95% purity for reliable use.
Applications
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Bioconjugation: Acts as a flexible linker in biomolecule modification.
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Polymer and Material Science: Introduces PEG functionality into polymer systems.
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Drug Delivery: Serves as a modular intermediate in therapeutic design.
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Probe Development: Builds multifunctional intermediates for imaging and diagnostics.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Remove Boc under mild acidic conditions; prepare fresh solutions for derivatization.
This product integrates amide protection, hydroxyl functionality, and PEG solubility in a compact scaffold, specifically providing a versatile building block for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
