t-Boc-N-Amido-PEG15-amine
This product is a high-purity PEG derivative with a Boc-protected amine group and a PEG15 spacer, specifically designed for controlled release of primary amines in bioconjugation and surface modification.
Key Features and Benefits
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Boc-Protected Amine: Provides a stable, temporary protecting group that can be removed under mild acidic conditions to yield a free primary amine
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PEG15 Spacer: Enhances solubility, provides long hydrophilic spacing, and reduces steric hindrance
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Amido Linkage: Ensures stability and controlled reactivity during synthetic processes
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High Purity: Suitable for advanced bioconjugation, drug delivery, and material science applications
Applications
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Amide bond formation with biomolecules after Boc deprotection
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Spacer for antibody–drug conjugates and peptide modification
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Linker in polymer–drug conjugates for improved solubility and circulation
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Surface modification of nanoparticles, hydrogels, and biomaterials
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Remove Boc with mild acids (e.g., TFA). Avoid repeated freeze–thaw cycles
This product provides a Boc-protected amine on a PEG15 spacer, specifically enabling controlled deprotection and efficient conjugation with enhanced solubility and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
