Boc-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker, and the Val-Ala peptide is specifically cleaved by Cathepsin B. The Boc group can be removed under acidic conditions. PNP is a good leaving group. Can be used to synthesize antibody-drug conjugates (ADCs).
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
