Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine (CAS: 525583-49-7) is a flexible and versatile PEG-based linker designed for bioconjugation and drug development. It features a Boc-protected amine group and a free amino group, both of which accordingly support efficient chemical reactions. The PEG₃ spacer enhances water solubility and reduces steric hindrance, ensuring compatibility with various biological and chemical systems.
Key Features:
- Dual Amino Functionality:
- Free Amino Group: Reacts with carboxylic acids, activated esters, aldehydes, and ketones to form stable bonds.
- Boc-Protected Amine: Easily deprotects under mild acidic conditions, exposing another reactive amine for further modifications.
- PEG₃ Spacer:
- Improves solubility in aqueous environments.
- Enhances molecular flexibility while minimizing steric interference.
Applications:
- Bioconjugation:
- Links biomolecules such as proteins, peptides, and antibodies, enabling efficient labeling and functionalization.
- Drug Development:
- Serves as a key linker in creating antibody-drug conjugates (ADCs) and other precision-targeted therapies.
Handling and Storage:
- Molecular Formula: C₁₇H₃₅N₃O₆
- Molecular Weight: 377.48 g/mol
- Purity: ≥95%
- Storage: Keep at -20°C in a cool, dry, and dark environment to maintain stability.
In summary, this product is a reliable and efficient tool for bioconjugation, chemical synthesis, and pharmaceutical research. Its dual functionality and enhanced solubility make it ideal for advanced molecular designs and innovative therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
