Boc-Aminooxyacetamide-PEG2-azide contains an azide and a bocaminooxy end group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. After de-Boc, the resulting free oxyamine group can react with an aldehyde to form a reversible oxime bond. If reduced, the oxime can be converted to a stable carbon-N bond. The PEG spacer increase the solubility of the resulting complex in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
