Boc-aminooxy-ethyl-SS-propanol
This product is a bifunctional reagent featuring a Boc-protected aminooxy group, a cleavable disulfide bond, and a terminal hydroxyl. It specifically offers orthogonal reactivity, redox sensitivity, and versatility for bioconjugation and drug delivery.
Key Features and Benefits
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Boc-Protected Aminooxy: Enables selective oxime ligation after deprotection.
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Disulfide Bond: Cleavable under reducing conditions for controlled release.
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Hydroxyl Group: Provides a site for additional derivatization.
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Orthogonal Reactivity: Supports multifunctional bioconjugation strategies.
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High Purity: Produced to ≥95% for reliable research use.
Applications
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Bioconjugation: Links biomolecules through oxime ligation and cleavable disulfide chemistry.
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Drug Delivery: Creates redox-sensitive linkers for controlled release systems.
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Nanoparticle Modification: Functionalizes carriers with responsive linkers.
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Crosslinking: Builds reversible or modular biomaterial scaffolds.
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Chemical Biology: Useful in labeling and probe design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Prepare fresh solutions; disulfides are sensitive to reducing agents.
This product combines oxime ligation capability with a redox-cleavable disulfide, making it an especially powerful tool for bioconjugation and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
