Bis-PEG25-TFP ester
This product is a homobifunctional PEG linker containing two tetrafluorophenyl (TFP) ester groups connected by a PEG25 spacer. It enables efficient amine conjugation at both ends, specifically providing a long, flexible, and highly soluble crosslinker for bioconjugation and material modification.
Key Features and Benefits
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Dual TFP Esters: React efficiently with primary amines to form stable amide bonds.
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PEG25 Spacer: Provides extended length, solubility, and biocompatibility.
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Homobifunctional Design: Allows symmetric crosslinking of amine-containing biomolecules.
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Long-Chain PEG: Reduces steric hindrance and improves aqueous solubility.
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High Purity: Ensures reliable and reproducible conjugation results.
Applications
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Bioconjugation: Crosslinks proteins, peptides, or small molecules via amine coupling.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides long PEG scaffolds for therapeutic conjugates.
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Material Science: Functionalizes polymers, nanoparticles, and surfaces with PEGylation.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product combines two reactive TFP ester groups with a long PEG25 spacer, specifically offering a highly soluble crosslinker for advanced bioconjugation and PEGylation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
