Bis-PEG23-endo-BCN
This product is a homobifunctional PEG linker featuring two endo-bicyclononyne (BCN) groups specifically connected by a long PEG23 spacer. This design enables catalyst-free SPAAC click chemistry with azides while providing excellent solubility, flexibility, and spacing for bioconjugation, nanomaterials, and drug delivery applications.
Key Features and Benefits:
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Dual endo-BCN Groups: Support rapid copper-free SPAAC click reactions with azides.
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PEG23 Spacer: Offers long-chain solubility, hydrophilicity, and steric separation.
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Symmetric Design: Facilitates homobifunctional conjugation.
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Bioorthogonal Reactivity: Enables selective, catalyst-free bioconjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules via dual BCN handles.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEGylated scaffolds with bioorthogonal reactivity.
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Nanomaterials: Functionalizes polymers and nanoparticles for advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect BCN groups from prolonged light exposure.
This product integrates dual SPAAC-ready BCN groups with a long PEG23 spacer, specifically offering solubility, flexibility, and bioorthogonal functionality for advanced conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
