Bis-PEG1-PFP ester
This product is a homobifunctional PEG linker containing two pentafluorophenyl (PFP) ester groups connected by a PEG1 spacer. It enables efficient amine conjugation at both ends, specifically offering a compact and reactive crosslinker for bioconjugation and material modification.
Key Features and Benefits
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Dual PFP Esters: React efficiently with primary amines to form stable amide bonds.
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PEG1 Spacer: Provides compact spacing with solubility enhancement.
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Homobifunctional Design: Enables symmetric crosslinking of amine-containing biomolecules.
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High Reactivity: PFP esters offer greater stability and reactivity compared to NHS esters.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Crosslinks proteins, peptides, or small molecules through amine coupling.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEGylated scaffolds with reactive handles.
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Material Science: Functionalizes nanoparticles, polymers, and surfaces with PEGylation.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product combines two reactive PFP ester groups with a compact PEG1 spacer, specifically offering a soluble and efficient linker for advanced bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
