Biotin-Poly(L-Lysine), MW 8.2K is a biotin-functionalized cationic poly(amino acid) based on poly(L-lysine). It combines an amine-rich PLL chain with biotin functionality specifically for avidin recognition, bioconjugation, and biomaterial research.
Key Features and Benefits
- Cationic Poly(amino acid): Poly(L-lysine) provides positively charged primary amine groups for electrostatic interactions and functionalization.
- MW 8.2K: Provides a lower molecular weight PLL chain with multiple lysine residues and primary amine functionality.
- Biotin Functionality: Provides biotin for high-affinity noncovalent recognition by avidin and streptavidin proteins.
- Avidin-Streptavidin Recognition: Supports strong biotin-mediated interactions with compatible avidin- and streptavidin-containing systems.
- Primary Amine-Rich Structure: Lysine side chains specifically provide multiple primary amines for electrostatic interactions and additional functionalization.
- Multifunctional Polymer Platform: Combines cationic PLL properties with biotin-mediated molecular recognition in one polymer.
- Bioconjugation Platform: Supports development of biotin-mediated conjugates, assemblies, and functional biomaterial systems.
Applications
- Biotin-Avidin Binding: Supports high-affinity noncovalent interactions with avidin, streptavidin, and related biotin-binding proteins.
- Bioconjugation: Enables development of biotin-mediated conjugates with compatible biomolecules, proteins, ligands, and functional materials.
- Polymer Functionalization: Provides biotin functionality specifically for incorporating PLL into avidin- or streptavidin-based systems.
- Nanoparticle Functionalization: Supports biotin-mediated modification and assembly of compatible nanoparticle systems.
- Surface Modification: Enables development of biotin-functionalized cationic coatings and surfaces for research applications.
- Biomolecular Complexation: The cationic PLL backbone supports electrostatic interactions with compatible negatively charged biomolecules and materials.
- Drug Delivery: Supports development of functional polymer conjugates and delivery systems for research applications.
- Biomaterial Research: Supports development of biotin-functionalized polymers, surfaces, assemblies, and related biomaterials.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
Biotin-Poly(L-Lysine), MW 8.2K combines an amine-rich cationic PLL chain with biotin functionality and specifically supports avidin-streptavidin recognition, bioconjugation, surface modification, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.