Biotin-PEG8-alcohol
This product is a heterobifunctional linker featuring a biotin tag, an eight-unit PEG spacer, and a terminal hydroxyl group. The biotin moiety specifically binds strongly to streptavidin, avidin, and NeutrAvidin, while the hydroxyl group serves as a versatile handle for further chemical modification. The PEG8 spacer improves solubility, flexibility, and biotin accessibility, making this reagent especially valuable for bioconjugation, probe development, and affinity-based applications.
Key Features and Benefits
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Biotin Tag: Ensures high-affinity binding to streptavidin and avidin systems.
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Hydroxyl Group: Provides a modifiable site for additional derivatization.
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PEG8 Spacer: Enhances solubility, spacing, and reduces steric hindrance.
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Versatile Design: Supports flexible conjugation strategies.
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High Purity: Produced to ≥95% purity for reproducible results.
Applications
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Affinity Capture: Immobilizes biomolecules on streptavidin-coated beads, plates, or chips.
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Bioconjugation: Provides a biotin handle for labeling and detection.
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Probe Development: Builds biotinylated probes for imaging and diagnostics.
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Drug Delivery: Functions as a PEGylated linker for targeted delivery systems.
Storage and Handling
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Storage: Store at –20 °C in a sealed, moisture-free container.
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Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.
This product combines strong biotin binding with hydroxyl functionality on a PEG8 backbone, providing an especially reliable tool for bioconjugation and assay development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
