Biotin-PEG8-acid
This product is a heterobifunctional PEG8 linker with a biotin group and a terminal carboxylic acid. The PEG8 spacer provides hydrophilicity, flexibility, and medium-range spacing, while the biotin enables strong binding to avidin/streptavidin systems for targeted bioconjugation and labeling.
Key Features and Benefits:
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Biotin Moiety: Ensures high-affinity binding to avidin and streptavidin proteins.
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Carboxylic Acid Group: Couples efficiently with amines for stable amide bond formation.
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PEG8 Spacer: Provides solubility, reduced steric hindrance, and flexible spacing.
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High Purity: Guarantees reproducibility in sensitive conjugation workflows.
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Dual Functionality: Combines affinity binding with versatile carboxyl reactivity.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.
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Bioconjugation: Enables dual-functional conjugation strategies.
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Drug Delivery: PEGylated linker improves solubility, targeting, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain acid reactivity.
This product provides reliable biotin binding with a reactive carboxyl group and PEG8 spacing, making it especially valuable for labeling, conjugation, and targeted delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
