Biotin-PEG7-thiourea
This product is a heterobifunctional linker containing a biotin tag, a PEG7 spacer, and a thiourea group. The biotin ensures strong, specific binding to streptavidin and avidin systems, while the PEG7 chain improves solubility and reduces steric hindrance. The thiourea group offers stable conjugation chemistry, specifically making this reagent highly useful for bioconjugation and probe development.
Key Features and Benefits
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Biotin Tag: Provides strong binding affinity to streptavidin, avidin, and NeutrAvidin.
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PEG7 Spacer: Enhances solubility, flexibility, and accessibility of the biotin moiety.
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Thiourea Group: Adds a stable and versatile conjugation handle.
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Dual Reactivity: Combines affinity capture with chemical modification.
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High Purity: Produced to ≥95% purity for reproducible results.
Applications
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Affinity Capture: Immobilizes biotinylated molecules on streptavidin-coated beads, plates, or surfaces.
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Bioconjugation: Couples biomolecules through thiourea chemistry with minimal steric hindrance.
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Probe Development: Builds multifunctional probes for imaging, pull-down assays, and diagnostics.
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Drug Delivery: Serves as a linker in targeted delivery platforms.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Dissolve freshly in dry solvent before use; avoid repeated freeze–thaw cycles.
This product integrates biotin affinity binding with thiourea conjugation chemistry in a solubilizing PEG7 backbone, making it an especially versatile tool for capture, labeling, and probe design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.