Biotin-PEG4-Hydrazide
This product is a high-purity biotinylation reagent featuring a hydrazide functional group for conjugation with aldehydes and ketones, connected by a PEG4 spacer that specifically enhances solubility and reduces steric hindrance.
Key Features and Benefits
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Biotin Moiety – Provides strong, specific binding to streptavidin and avidin systems.
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Hydrazide Group – Reacts selectively with aldehydes and ketones to form stable hydrazone linkages.
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PEG4 Spacer – Improves solubility, flexibility, and accessibility of the biotin tag.
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High Purity – Ensures reliability for bioconjugation, labeling, and detection applications.
Applications
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Biotinylation of oxidized glycoproteins and polysaccharides
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Labeling of aldehyde- or ketone-containing biomolecules
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Probe and assay development in diagnostics
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Linker for drug delivery and capture systems
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO) or aqueous buffer as needed. Avoid repeated freeze–thaw cycles.
This product enables efficient conjugation of biotin to aldehyde- and ketone-containing biomolecules via hydrazone formation. The PEG4 spacer specifically enhances solubility and reduces steric hindrance, making it ideal for bioconjugation, assay development, and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
