Biotin-PEG4-acid
This product is a heterobifunctional linker featuring a biotin moiety for high-affinity avidin/streptavidin binding and a terminal carboxylic acid for amide coupling. The PEG4 spacer provides solubility, flexibility, and balanced spacing, making it especially effective in bioconjugation, labeling, and drug delivery applications.
Key Features and Benefits:
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Biotin Moiety: Ensures strong, specific avidin/streptavidin interactions.
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Carboxylic Acid: Couples efficiently with primary amines.
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PEG4 Spacer: Provides hydrophilicity and steric accessibility.
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Dual Reactivity: Combines biotin affinity with conjugation chemistry.
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High Purity: Ensures consistent, reproducible results.
Applications:
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Bioconjugation: Links biomolecules through biotin-streptavidin systems and amide bonds.
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Probe Development: Builds biotinylated probes for imaging and diagnostics.
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Drug Delivery: Provides PEGylated scaffolds with strong biotin affinity.
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Surface Functionalization: Introduces biotin handles to polymers and nanoparticles.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) for efficient coupling.
This product integrates strong biotin binding with carboxyl functionality in a PEG4 scaffold, specifically providing solubility and dual reactivity for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
